BDBM102349 US10562854, No. E33::US8536181, E33::US9278930, E33

SMILES CN(CC(O)=O)Cc1ccn(c(=O)c1O)S(=O)(=O)c1ccc(C)cc1

InChI Key InChIKey=SUGKSHMYQZJYRO-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 102349   

TargetVascular endothelial growth factor A(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102349(US10562854, No. E33 | US8536181, E33 | US9278930, ...)
Affinity DataIC50:  2.10E+3nMAssay Description:ELISA assay using VEGF.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102349(US10562854, No. E33 | US8536181, E33 | US9278930, ...)
Affinity DataIC50:  2.10E+3nMAssay Description:VEGF: HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following ove...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102349(US10562854, No. E33 | US8536181, E33 | US9278930, ...)
Affinity DataIC50:  2.10E+3nMAssay Description:HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Aerpio Therapeutics

US Patent
LigandPNGBDBM102349(US10562854, No. E33 | US8536181, E33 | US9278930, ...)
Affinity DataIC50:  2.10E+3nMAssay Description:HEK293 cells are seeded in 96-well poly-lysine coated plates at 20,000 cells per well in DMEM (10% FBS, 1% NEAA, 0.1% glutamine). Following overnight...More data for this Ligand-Target Pair
In DepthDetails US Patent